Table of Contents
What is 800CW?
IRDye 800CW near-infrared fluorescent dyes can be used for protein and antibody labeling, or nucleic acid applications with high labeling density.
What is infrared dye?
Near infrared dyes show light absorption in the near infrared area of 700-2000 nm. Their intense absorption normally originates from a charge transfer of an organic dye or metal complex.
How long does ICG dye last?
Because of the high protein content of lymph, ICG accumulates in the lymphatic pathways and lymph nodes. ICG-dyed lymph nodes become visible 5 minutes after light excitation and remain visible for around 60 minutes 10 . The intravascular half-life of ICG is 3 – 4 minutes; elimination occurs through the liver 11 .
What does infrared do to the human body?
Since infrared therapy enhances and improves circulation in the skin and other parts of the body, it can bring oxygen and nutrients to injured tissues, promoting healing. It helps ease pain, relieve inflammation, and protect against oxidative stress.
Is infrared treatment safe?
Infrared therapy technology allows people to harness the benefits of the sun, without being exposed to harmful ultraviolet rays. Also, infrared therapy is safe and effective, without adverse side effects. As a matter of fact, infrared light is safe and is used even for infants in the neonatal intensive care.
What is ICG dye used for?
Indocyanine green injection is a medical dye used in tests to help determine the cardiac (heart) output, liver function, and blood flow in the liver. It is also used to help certain parts of the eye to become more visible during medical procedures such as angiography.
What are the negative effects of infrared?
IR raises the internal temperature of the eye, virtually “baking” it. Prolonged IR exposure can lead cataracts, corneal ulcers, and retinal burns. Don’t stare at the sun! The infrared radiation in the sunlight damages skin.
Is ICG a dye?
What is IRDye 800CW dye?
IRDye 800CW dye is characterized by high water solubility and salt tolerance, low non-specific binding to cellular components, and a high signal-to-noise ratio. IRDye 800CW dye-conjugated agents and probes are currently propelling more than a dozen Phase I or Phase II clinical trials, more than any other near-infrared fluorescent dye.
Which form of IRDye 800CW is an ideal control for labeling?
Carboxylate (non-reactive) form of IRDye 800CW is an ideal control. Note: The carboxylate dye has no reactive group and cannot be used for labeling.
What is IRDye 800CW NHS ester?
IRDye 800CW NHS Ester will Label Primary and Secondary Amines. IRDye infrared dyes from LI-COR Biosciences are available for researchers developing applications using near-infrared (NIR) fluorescence.
What is the best control for IRDye 800CW in assays?
Assays that use IRDye 800CW conjugates (such as in vivo imaging and cell binding assays) may require a “dye-only” control for potential effects or retention of the dye. Carboxylate (non-reactive) form of IRDye 800CW is an ideal control.